Mal-Amide-PEG4-Glu-Gly-Cit-PAB-MMAE comprises a cathepsin-cleavable Glu-Gly-Cit (EGCit) peptide, a PABC linker, MMAE payload, and a maleimide group reactive toward thiol groups. This compound shows strong stability in the bloodstream and discreet, traceless intracellular payload release.
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