Mesylate-PEG-t-butyl ester, MW 2,000 functions as a polyPEG reagent containing a mesyl group and a t-butyl protecting group. The mesyl group serves as a good leaving group for nucleophilic substitution reactions. The t-butyl is an acid labile protecting group. Upon removal, the carboxylic acid can react with primary amines. The hydrophilic 2k PEG polymer increases the water solubility of the compound in aqueous media.
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