DBCO-PEG8-Val-Cit-PAB-OH is a linker intermediate featuring a DBCO group, a Val-Cit dipeptide, and a PAB motif. The DBCO group is a click chemistry handle which readily reacts with azide groups on a target molecule, while the Val-Cit dipeptide is a protease-cleavable motif which releases a given warhead into cells via an elimination mechanism within the PAB structure.
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