Broad class of PEGylated, water-soluble reagents for simple and efficient biotin labeling of antibodies, proteins and other primary amine-containing macromolecules. PEGylation imparts water solubility to the biotinylated molecule, helping to prevent aggregation of biotinylated antibodies stored in solution.
Biotin-PEG-Oxyamine and Biotin Hydrazide are aldehyde-reactive biotinylation reagents that contain PEG spacer arms for increased hydrophilicity.
A class of biotin compounds containing a PEG spacer arm and a terminal primary amine for conjugation via EDC and other crosslinker methods. PEGylation increases water solubility to the biotinylated molecule.
Cleavable biotinylation reagents for selective enrichment of azide, alkyne, NHS active ester, oxyamine, … containing biomolecules.
Azido-, alkyne-, and DBCO containing biotinylation reagents for bioconjugation, biolabeling and chemical modification. Biotin can be subsequently detected with streptavidin, avidin or NeutrAvidin® biotin-binding protein.
Desthiobiotin is a single-ring, sulfur-free analog of biotin that provides soft-release elution from streptavidin.
A class of biotin labeling reagents such as Biotin-PEG-Mal and Biotin-HPDP used to specifically biotinylate antibodies and other biomolecules at sulfhydryl groups.
Methyltetrazine-activated biotinylation reagents react with TCO-containing compounds via a Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond.
Biotin labeling regents that contain hydroxyl group, halogen (ie. Iodide)